The Los Angeles Rams (favored by 3.5 points) face the San Francisco 49ers in a crucial NFC West matchup on Monday Night Football. Both teams are looking to bounce back from disappointing losses in Week 9.

Los Angeles Rams Overview:

• Coming off a loss to the Titans where they scored under 20 points
• Matthew Stafford questionable with an ankle sprain from last week's game
• Will potentially debut Von Miller on defense, while OBJ likely debuts next week
• Need their offense to get back on track after struggling against Tennessee

San Francisco 49ers Overview:

• Lost to Cardinals last week despite Arizona missing Kyler Murray
• Struggled offensively, scoring only 17 points
• Need to improve run defense after allowing multiple TDs to James Conner
• Playing second straight division game at home

Key Factors:

• Stafford's ankle injury status could significantly impact Rams' offensive effectiveness
• Integration of Von Miller with Aaron Donald on Rams' defensive line
• 49ers must improve run defense after struggling last week
• Home field advantage for San Francisco

The matchup's outcome likely hinges on Stafford's health status and how well the 49ers can contain the Rams' offense. While Los Angeles enters as favorites, San Francisco's home field advantage and motivation to bounce back make this an intriguing divisional clash.

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