
White Sox vs Guardians April 21: Betting Lines and Preview as Cleveland Seeks Sweep
After two rain-delayed days, the Cleveland Guardians aim to sweep the Chicago White Sox in their series finale on Thursday, April 21st at 1:10 p.m.
The Guardians dominated Wednesday's doubleheader, winning 11-1 and 2-1. Jose Ramirez hit a grand slam in game one, while the pitching staff held Chicago's potent offense to just two total runs across both games.
Game Details:
- Time: 1:10 p.m. ET
- Odds: White Sox -140, Guardians +117
- Run Line: Guardians +1.5 (-140)
- Over/Under: 8 runs
Pitching Matchup:
- White Sox: Dylan Cease (2-0, 1.69 ERA, 16 K, 0.94 WHIP)
- Guardians: Zach Plesac (0-1, 1.64 ERA)
Key Players to Watch:
- White Sox: Andrew Vaughn (.310/.375/.552, 2 HR, 6 RBI)
- Guardians: Jose Ramirez (.429/.479/.881, 4 HR, 20 RBI)
Head-to-Head Notes:
- Luis Robert is 5-for-10 against Plesac
- Jose Abreu and Tim Anderson have combined for 3 HR in 35 at-bats vs Plesac
Despite Cleveland's two wins Wednesday, the White Sox enter as favorites behind Cease's strong start to the season. The Guardians will rely on their hot-hitting Ramirez and solid pitching to complete the sweep against their division rivals.
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