The Columbus Crew host Nashville SC at Lower.com Field on Wednesday at 7:30 p.m. ET in a key Eastern Conference matchup. Both teams are vying for top-4 positions after weekend victories.

Columbus holds a perfect 2-0-0 record against Nashville historically, winning both matches 2-0. Their most recent meeting saw Columbus advance in the 2020 MLS Cup Playoffs with two extra-time goals.

Key Updates:

• Lucas Zelarayan set a Crew record with his 4th free-kick goal this season in Saturday's 2-1 win over NYCFC
• Eloy Room returns in goal after Curacao's Gold Cup exit
• Harrison Afful back from suspension
• Still missing: Zardes, Fraser, Molina, Etienne Jr. (Gold Cup duty)

Nashville Notes:

• Coming off 5-1 win vs Chicago Fire
• Hany Mukhtar scored hat-trick in 6 minutes
• Missing defenders Zimmerman and Johnston (Gold Cup)
• Unbeaten in 15 of last 16 matches
• Only 3 road games this season (2D, 1L)

Betting Lines:

• Columbus ML: +165 (-0.5 +135)
• Nashville ML: +175 (-0.5 -145)
• Draw: +235
• Total Goals 2.5: Over -115, Under -105
• First to Score: Crew +100, Nashville -105, No Goals +600

Analysis: Columbus holds strong home advantage with 18-1-2 record in last 21 home games. Zelarayan's set-piece ability gives them a dangerous weapon. The Crew have scored 11 goals in their last 5 home matches and could capitalize early against a Nashville team playing their first road game since June 18.

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