
McNeese vs Purdue Betting Lines: Boilermakers Open as 7.5-Point Favorites in Second Round
The #12 McNeese Cowboys will face #4 Purdue Boilermakers in a highly anticipated NCAA Tournament second-round matchup in Providence, RI. Purdue opens as a 7.5-point favorite with -325 moneyline odds, while McNeese sits at +260 to advance.

Basketball player celebrating victory pose
Key Betting Lines:
- Spread: Purdue -7.5
- Moneyline: Purdue -325 / McNeese +260
- Total: 139.5 (Over/Under -110)
Recent Performance:
- McNeese (28-6) stunned #5 Clemson 69-67 as 7.5-point underdogs
- Purdue (23-11) easily handled #13 High Point in their opener
- Purdue is 14-1 against teams outside KenPom's top 50 this season
Notable Stats:
- McNeese's Christian Shumate: 13 points, 11 rebounds vs Clemson
- Brandon Murray: Team-high 21 points off bench
- Purdue's Trey Kauffman-Renn: 21 points, 8 rebounds vs High Point

March Madness Selection Show
Head-to-Head Context:
- Only common opponent: Alabama
- McNeese lost 72-64 (away)
- Purdue won 87-78 (home)
The winner advances to the Sweet 16, marking Purdue's potential second straight appearance or McNeese's first in program history. Purdue's Final Four odds currently stand at +1000.