The Cleveland Guardians (65-56) face the San Diego Padres (68-57) in the finale of their two-game interleague series at Petco Park, with first pitch at 4:10 pm ET.

The Guardians won game one 3-1, powered by home runs from Oscar Gonzalez and Andres Gimenez. Jose Ramirez added an RBI single in the eighth. Aaron Civale and the bullpen combined to limit the Padres to one run on six hits.

Betting Odds:

• Padres: -158
• Guardians: +134
• Run line: Guardians +1.5 (-160)
• Over/Under: 7.5 runs

Pitching Matchup:

• Guardians: Cal Quantrill (9-5, 3.77 ERA, 1.22 WHIP)
• Padres: Blake Snell (5-6, 3.76 ERA, 1.30 WHIP)

Key Points:

• Jose Ramirez hits .333 with a HR against Snell lifetime
• Padres batting just 4-for-23 against Quantrill historically
• Juan Soto (back) questionable after missing game one
• Guardians looking to extend AL Central lead
• Padres clinging to final NL Wild Card spot

The Guardians have a good opportunity to sweep with Quantrill on the mound, especially if Soto remains out. The Padres' offense ranks 15th in runs per game (4.40) and struggles more at home (3.93). A strong start from Quantrill could help Cleveland secure the series sweep.

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