Tigers vs. Guardians May 21: Betting Odds and Preview at Progressive Field

Tigers vs. Guardians May 21: Betting Odds and Preview at Progressive Field

By Michael Harrison

February 16, 2025 at 08:32 AM

The Detroit Tigers (13-26) face the Cleveland Guardians (17-19) in game two of their three-game series at Progressive Field on Saturday, May 21, with first pitch at 6:10 pm ET. The Guardians won the opener 6-1 behind Jose Ramirez's strong performance.

Game Details & Odds:

  • Moneyline: Guardians -190, Tigers +160
  • Run line: Tigers +1.5 (-142)
  • Over/Under: 8 runs
  • Location: Progressive Field, Cleveland

Pitching Matchup:

  • Tigers: Alex Faedo (0-1, 2.87 ERA, 1.28 WHIP)
  • Guardians: Shane Bieber (1-2, 3.72 ERA, 1.27 WHIP)

Key Stats:

  • Guardians offense: 7th in MLB (4.66 runs/game)
  • Tigers offense: Last in MLB (2.76 runs/game)
  • Tigers road record: 4-13
  • Guardians home record: 8-7

Key Players:

  • Jose Ramirez (CLE): .287/.380/.588, 9 HR, 37 RBI
  • Miguel Cabrera (DET): .276/.321/.390, 3 HR, 14 RBI

Betting Analysis: The Guardians are favored at home with their ace on the mound. Cleveland has dominated this matchup recently, going 15-5 in their last 20 home games against Detroit. The Tigers continue to struggle on the road this season with a 4-13 record away from home.

The pitching matchup favors Cleveland with Shane Bieber facing the league's lowest-scoring offense. The Guardians look to secure the series win and improve their position in the AL Central race.

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