
Tigers vs. Guardians May 21: Betting Odds and Preview at Progressive Field
The Detroit Tigers (13-26) face the Cleveland Guardians (17-19) in game two of their three-game series at Progressive Field on Saturday, May 21, with first pitch at 6:10 pm ET. The Guardians won the opener 6-1 behind Jose Ramirez's strong performance.
Game Details & Odds:
- Moneyline: Guardians -190, Tigers +160
- Run line: Tigers +1.5 (-142)
- Over/Under: 8 runs
- Location: Progressive Field, Cleveland
Pitching Matchup:
- Tigers: Alex Faedo (0-1, 2.87 ERA, 1.28 WHIP)
- Guardians: Shane Bieber (1-2, 3.72 ERA, 1.27 WHIP)
Key Stats:
- Guardians offense: 7th in MLB (4.66 runs/game)
- Tigers offense: Last in MLB (2.76 runs/game)
- Tigers road record: 4-13
- Guardians home record: 8-7
Key Players:
- Jose Ramirez (CLE): .287/.380/.588, 9 HR, 37 RBI
- Miguel Cabrera (DET): .276/.321/.390, 3 HR, 14 RBI
Betting Analysis: The Guardians are favored at home with their ace on the mound. Cleveland has dominated this matchup recently, going 15-5 in their last 20 home games against Detroit. The Tigers continue to struggle on the road this season with a 4-13 record away from home.
The pitching matchup favors Cleveland with Shane Bieber facing the league's lowest-scoring offense. The Guardians look to secure the series win and improve their position in the AL Central race.
Related Articles

NBA Betting Guide: Top Picks and Analysis for February 4, 2022
