No. 5 Indiana's Perfect Record Faces Major Test at No. 2 Ohio State: Prediction & Latest Odds
The #5 Indiana Hoosiers (10-0) visit the #2 Ohio State Buckeyes (9-1) at Ohio Stadium on Saturday, November 23, with kickoff set for 12:00 PM ET on FOX.
Football player carrying ball downfield
Indiana enters as the season's biggest surprise, starting 10-0 for the first time in program history under first-year coach Curt Cignetti. The Hoosiers aim to snap a 28-game losing streak against Ohio State dating back to 1991.
Sharp money has moved the line from Ohio State -12.5 to -10.5, with the over/under at 52.5. While only 5% of bets favor Indiana's moneyline, they're attracting 57% of the handle.
Key Matchup Factors:
- Indiana's defense allows just 14 points per game
- Ohio State averages 37.8 points and 7.2 yards per play
- Buckeyes lost two key offensive linemen to season-ending injuries
- Indiana's Mikail Kamara leads Big Ten with 9.5 sacks
- Ohio State's defense ranks #1 nationally (10.3 points allowed)
Injured player quote
Current Betting Lines:
- Spread: Ohio State -10.5 (-110) | Indiana +10.5 (-110)
- Moneyline: Ohio State -380 | Indiana +300
- Total: 52.5 (Over/Under -110)
Historical Context:
- Ohio State leads series 79-12-5
- Buckeyes have won 30 straight meetings since 1988
- Last year: Ohio State won 23-3 as 19-point favorites
Prediction: Ohio State wins 31-23, but Indiana covers the spread. The combination of Indiana's strong defense, Ohio State's offensive line issues, and the sharp money movement suggests a competitive game.
Best Bet: Indiana +10.5 (-110)
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