NFL Week 16 Christmas Showdown: Colts vs Cardinals Betting Preview

NFL Week 16 Christmas Showdown: Colts vs Cardinals Betting Preview

By Michael Harrison

January 31, 2025 at 11:26 PM

The Indianapolis Colts (hot streak) face off against the Arizona Cardinals (struggling) in a crucial Week 16 Christmas night matchup in Glendale, with the Cardinals as 1-point home favorites.

Colts Analysis:

  • Won 5 of last 6 games, including 27-17 victory over Patriots
  • Jonathan Taylor leads potent rushing attack with 1,500+ yards
  • Carson Wentz showing improved decision-making with only 6 interceptions
  • Physical, ball-control offense has been key to recent success

Cardinals Analysis:

  • Coming off upset loss to Lions as 12-point favorites
  • Defense struggling, allowing 30+ points in consecutive games
  • Offense sputtered against Detroit, scoring just 12 points
  • Looking to avoid third straight loss

Keys to Victory:

  • Colts: Control time of possession through running game, avoid turnovers
  • Cardinals: Improve run defense, get offense back on track

The game features two potential playoff teams heading in opposite directions - the surging Colts relying on their ground game versus a Cardinals team trying to recapture their early-season form.

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