
NFL Week 16 Christmas Showdown: Colts vs Cardinals Betting Preview
The Indianapolis Colts (hot streak) face off against the Arizona Cardinals (struggling) in a crucial Week 16 Christmas night matchup in Glendale, with the Cardinals as 1-point home favorites.
Colts Analysis:
- Won 5 of last 6 games, including 27-17 victory over Patriots
- Jonathan Taylor leads potent rushing attack with 1,500+ yards
- Carson Wentz showing improved decision-making with only 6 interceptions
- Physical, ball-control offense has been key to recent success
Cardinals Analysis:
- Coming off upset loss to Lions as 12-point favorites
- Defense struggling, allowing 30+ points in consecutive games
- Offense sputtered against Detroit, scoring just 12 points
- Looking to avoid third straight loss
Keys to Victory:
- Colts: Control time of possession through running game, avoid turnovers
- Cardinals: Improve run defense, get offense back on track
The game features two potential playoff teams heading in opposite directions - the surging Colts relying on their ground game versus a Cardinals team trying to recapture their early-season form.

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