NFL Week 12 Picks: Expert's Best Bets Against the Spread
Week 12 features twelve games with six teams on bye. Double-digit favorites have gone 5-0 against the spread this season, making the Commanders (-10.5) and Chiefs (-10.5) potentially attractive picks.
Football player celebrating a touchdown
Best NFL Week 12 Picks Against the Spread:
Packers -3 vs 49ers (-115)
- 49ers struggling with a 5-5 record
- Purdy dealing with shoulder issues
- Nick Bosa questionable
- Packers rank 4th in takeaways
- Cold weather favors Green Bay
- 49ers poor 1-3 road ATS record
Cardinals +1 vs Seahawks (-115)
- Cardinals coming off bye week
- Kyler Murray playing efficiently
- James Conner running strong
- Seattle's rush defense ranks 27th
- Cardinals have won four straight
- Geno Smith 1-5 ATS at home
Eagles -3 vs Rams (-105)
- Eagles won last three vs Rams
- 4-1 ATS on road this season
- Strong rushing attack with Barkley and Hurts
- AJ Brown boosts offensive potential
- Eagles allow least passing yards per attempt
- Rams O-line dealing with injuries
The odds listed are from ESPN BET as of November 22, 2024. Lines may vary by sportsbook and are subject to change.
[Tweet content showing Kyler Murray's rushing TD]
Always remember to bet responsibly and within your means. These picks are for entertainment purposes only.
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