The San Francisco 49ers will face the Green Bay Packers in a crucial NFL Divisional Playoff matchup at Lambeau Field. The Packers enter as 5.5-point favorites after securing the NFC's top seed and a first-round bye.

The 49ers advanced by upsetting the Dallas Cowboys in the Wild Card round, with their defense holding Dallas to just 17 points. Their biggest challenge will be containing Aaron Rodgers while dealing with injuries to key defensive players Nick Bosa and Fred Warner.

The well-rested Packers aim to protect Rodgers, who was sacked just once in their previous meeting this season - a game Green Bay won on a last-second field goal. The combination of home field advantage and extra rest could prove decisive.

Key Factors:

• Jimmy Garoppolo's health and performance after sustaining a sprained throwing shoulder against Dallas
• 49ers' ability to generate defensive pressure on Rodgers
• Packers' need to avoid self-inflicted errors despite being favored
• The status of injured 49ers defenders Bosa and Warner

This matchup features two of the NFL's most storied franchises, with the winner advancing to the NFC Championship Game. The Packers' superior quarterback play and healthier roster give them an edge, but their previous meeting this season proved these teams are closely matched.

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