Guardians vs White Sox September 21: Critical AL Central Showdown Betting Preview

Guardians vs White Sox September 21: Critical AL Central Showdown Betting Preview

By Michael Harrison

March 1, 2025 at 10:16 PM

The Cleveland Guardians (81-67) face the Chicago White Sox (76-72) at Guaranteed Rate Field on Wednesday at 8:10 p.m., following their 10-7 extra-innings victory on Tuesday. The Guardians now lead the AL Central by five games with 14 remaining.

Betting Lines:

  • White Sox: -127 (Favorites)
  • Guardians: +112
  • Run line: Cleveland +1.5 (-193)
  • Over/Under: 7.5 runs

Pitching Matchup:

  • Guardians: Triston McKenzie (10-11, 3.08 ERA, 0.97 WHIP)
  • White Sox: Lance Lynn (7-5, 3.99 ERA, 1.07 WHIP)

Key Stats:

  • McKenzie: 167 strikeouts in 172.1 innings
  • Lynn: Has won 4 straight starts, allowing just 3 earned runs in 26.1 innings
  • Jose Ramirez vs Lynn: .345 with 4 HR in 29 at-bats
  • Seby Zavala vs McKenzie: 2 HR and 5 RBI in 6 at-bats

Game Impact:

  • Critical matchup for White Sox playoff hopes
  • Guardians can extend division lead to 6 games
  • Cleveland has won 8 of their last 10 games

This pivotal AL Central matchup features two hot pitchers, with Lynn's recent dominance facing a surging Guardians team. The White Sox must win to keep their division title hopes alive, while Cleveland looks to further cement their playoff position.

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