#20 Clemson Tigers face the Pittsburgh Panthers in a crucial ACC matchup on Saturday, November 16. Clemson enters as 11.5-point road favorites, with the total set at 52.5 points.

Clemson (7-2, 6-1 ACC) has found their rhythm after a Week 1 loss to Georgia. Quarterback Cade Klubnik has thrown 24 touchdowns with just four interceptions, while running back Phil Mafah has rushed for over 100 yards in four of his last five games. The Tigers' offense ranks third in the ACC, averaging 37.7 points per game.

The Tigers' defense has been equally impressive, ranking 12th nationally in third-down conversion rate. They're allowing minimal rushing yards and have shown particular strength in conference play, averaging 6.71 tackles for loss in ACC games.

Pitt (7-2) started the season 7-0 but has lost two straight games. The Panthers' offense has struggled recently, converting only 24% of third downs in their last four games. Starting quarterback Eli Holstein remains questionable for this matchup.

While Pitt's defense ranks 18th nationally in EPA/rush and averages 8 tackles for loss in ACC play, their recent offensive struggles are concerning.

Prediction: Clemson's strong defense and balanced offense should control this game. The Panthers' offensive woes and third-down conversion struggles will likely continue against Clemson's stout defense. Even if the game starts close, expect the Tigers to pull away.

Pick: Clemson -11.5 (-110)

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