The Cleveland Browns (3-2) face the undefeated Arizona Cardinals (5-0) in what promises to be an intriguing matchup. The Browns are coming off a wild 47-42 loss to the Chargers, while the Cardinals maintained their perfect record with a 17-10 victory over the 49ers.

Kyler Murray continues his MVP-caliber season, leading Arizona's top-5 offense with over 320 passing yards per game plus dangerous running ability. The Cardinals' defense has been quietly effective, holding four of five opponents to 20 points or less, though they'll miss Chandler Jones this Sunday.

The Browns' powerful rushing attack remains their strength, with Nick Chubb and Kareem Hunt combining for over 220 yards and three touchdowns last week. Baker Mayfield showed improvement with a 300+ yard passing performance, but Cleveland's defense raised concerns after allowing 47 points to the Chargers.

Key Factors:

• Cardinals are 5-0 with four wins by 7+ points
• Browns' run game remains elite despite recent loss
• Arizona's defense missing key player Chandler Jones
• Early East Coast game could challenge West Coast Cardinals
• Browns favored despite facing undefeated opponent

The Browns have a solid opportunity at home, with the early start time potentially affecting the traveling Cardinals. However, they'll need their defense to step up against Murray's high-powered offense to secure a victory.

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