2025 Indy 500: Expert Predictions, Race Time & Betting Odds Preview
The 109th Indianapolis 500 takes place Sunday, May 25, with the green flag dropping at 12:45 p.m. EDT. Pato O'Ward enters as the favorite, while rookie Robert Schwartzman makes history as the first rookie pole-sitter since 1983.

Two NASCAR cars racing on track
Key Race Details:
- Date: Sunday, May 25
- Start Time: 12:45 p.m. EDT
- Location: Indianapolis Motor Speedway
- Distance: 200 laps
- TV Coverage: FOX (starts 10 a.m. EDT)
Pre-Race Schedule:
- 12:24 p.m.: National anthem by Natalie Grant
- 12:29 p.m.: Drivers to cars
- 12:36 p.m.: "Back Home Again In Indiana" by Jim Cornelison
- 12:38 p.m.: Command to start engines by Roger Penske
- 12:45 p.m.: Green flag
Top Contenders and Odds:
- Alex Palou (+600): Four wins in five starts this season, leads series with 149 laps led
- Josef Newgarden: Seeking unprecedented third straight Indy 500 win but starting from back row
- Colton Herta (+2500): Strong dark horse candidate with top-10 finishes in three of last four races
Notable Storylines:
- Controversy surrounds Penske Racing after illegal modifications found on Newgarden and Power's cars
- Rookie Robert Schwartzman secured pole position but faces long odds as points standings leader
- Weather forecast shows slight chance of showers
Expert Pick: Alex Palou (+600)
- Current IndyCar Series points leader
- Two-time defending series champion
- Previous best Indy 500 finish: 2nd (2021)
- Starting position: 6th
- Qualifying speed: 231.4 mph
Dark Horse: Colton Herta (+2500)
- Youngest-ever IndyCar race winner
- Strong recent form
- Starting: Row 9
- Proven race-winning capability
Alternative betting options include top-three finishes and team winner markets, with Ganassi and Aaron McLaren co-favored at +320.